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Extracellular vesicles from the inflammatory microenvironment regulate the osteogenic and odontogenic differentiation of periodontal ligament stem cells by miR-758-5p/LMBR1/BMP2/4 axis

BACKGROUND: Extracellular vesicles (EVs) play a key role in constructing a microenvironment that favors the differentiation of stem cells. The present work aimed to determine the molecular mechanisms by which EV derived from inflammatory dental pulp stem cell (iDPSC-EV) influence periodontal ligamen...

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Detalles Bibliográficos
Autores principales: Yan, Chaoting, Li, Na, Xiao, Tong, Ye, Xiaying, Fu, Lin, Ye, Yu, Xu, Tao, Yu, Jinhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9103284/
https://www.ncbi.nlm.nih.gov/pubmed/35562763
http://dx.doi.org/10.1186/s12967-022-03412-9