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Mutated KIT Tyrosine Kinase as a Novel Molecular Target in Acute Myeloid Leukemia

KIT is a type-III receptor tyrosine kinase that contributes to cell signaling in various cells. Since KIT is activated by overexpression or mutation and plays an important role in the development of some cancers, such as gastrointestinal stromal tumors and mast cell disease, molecular therapies targ...

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Detalles Bibliográficos
Autores principales: Katagiri, Seiichiro, Chi, SungGi, Minami, Yosuke, Fukushima, Kentaro, Shibayama, Hirohiko, Hosono, Naoko, Yamauchi, Takahiro, Morishita, Takanobu, Kondo, Takeshi, Yanada, Masamitsu, Yamamoto, Kazuhito, Kuroda, Junya, Usuki, Kensuke, Akahane, Daigo, Gotoh, Akihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9103326/
https://www.ncbi.nlm.nih.gov/pubmed/35563085
http://dx.doi.org/10.3390/ijms23094694