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Mutated KIT Tyrosine Kinase as a Novel Molecular Target in Acute Myeloid Leukemia
KIT is a type-III receptor tyrosine kinase that contributes to cell signaling in various cells. Since KIT is activated by overexpression or mutation and plays an important role in the development of some cancers, such as gastrointestinal stromal tumors and mast cell disease, molecular therapies targ...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9103326/ https://www.ncbi.nlm.nih.gov/pubmed/35563085 http://dx.doi.org/10.3390/ijms23094694 |