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Unraveling enhanced brain delivery of paliperidone-loaded lipid nanoconstructs: pharmacokinetic, behavioral, biochemical, and histological aspects

Antipsychotics are accompanied by extrapyramidal side effects that deter treatment adherence and patient compliance. Paliperidone (PPD), an atypical (second-generation) antipsychotic recommended for managing schizophrenia presents biopharmaceutical challenges and pharmacological constraints which di...

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Detalles Bibliográficos
Autores principales: Rehman, Saleha, Nabi, Bushra, Javed, Amaan, Khan, Tahira, Iqubal, Ashif, Ansari, Mohammad Javed, Baboota, Sanjula, Ali, Javed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9103378/
https://www.ncbi.nlm.nih.gov/pubmed/35532148
http://dx.doi.org/10.1080/10717544.2022.2069880