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Ethosomal gel for rectal transmucosal delivery of domperidone: design of experiment, in vitro, and in vivo evaluation

Despite high efficiency of domperidone (DOM) in prophylaxis of emesis accompanied with radiotherapy and chemotherapy, it still can bother cancer patients by its powerful side effects and difficulty of its oral administration. The study was designed to develop and optimize DOM loaded ethosomal gel fo...

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Detalles Bibliográficos
Autores principales: Sakran, Wedad, Abdel-Rashid, Rania S., Saleh, Fatma, Abdel-Monem, Raghda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9103489/
https://www.ncbi.nlm.nih.gov/pubmed/35543451
http://dx.doi.org/10.1080/10717544.2022.2072542