Dynamic Phenomena and Complexation Effects in the α-Lithiation and Asymmetric Functionalization of Azetidines

In this work it is demonstrated that enantiomerically enriched N-alkyl 2-oxazolinylazetidines undergo exclusive α-lithiation, and that the resulting lithiated intermediate is chemically stable but configurationally labile under the given experimental conditions that afford enantioenriched N-alkyl-2,...

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Detalles Bibliográficos
Autores principales: Musci, Pantaleo, Colella, Marco, Altomare, Angela, Romanazzi, Giuseppe, Sheikh, Nadeem S., Degennaro, Leonardo, Luisi, Renzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9103493/
https://www.ncbi.nlm.nih.gov/pubmed/35566200
http://dx.doi.org/10.3390/molecules27092847

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9103493/
https://www.ncbi.nlm.nih.gov/pubmed/35566200
http://dx.doi.org/10.3390/molecules27092847

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