The inhibitory effect of boric acid on hypoxia-regulated tumour-associated carbonic anhydrase IX

Carbonic anhydrases (EC 4.2.1.1) catalyse the reversible hydration of CO(2) into bicarbonate and protons. As a hypoxia-sensitive and tumour-associated isoform, isoform CA IX, is significantly overexpressed in various malignancies, being a validated target for new anticancer/antimetastatic drugs. A m...

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Detalles Bibliográficos
Autores principales: Yusuf, Zainab Saad, Uysal, Tugba Kevser, Simsek, Ender, Nocentini, Alessio, Osman, Sameh Mohamed, Supuran, Claudiu T., Özensoy Güler, Özen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9103596/
https://www.ncbi.nlm.nih.gov/pubmed/35535546
http://dx.doi.org/10.1080/14756366.2022.2072837

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9103596/
https://www.ncbi.nlm.nih.gov/pubmed/35535546
http://dx.doi.org/10.1080/14756366.2022.2072837

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