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Natural LILRB1 D1-D2 variants show frequency differences in populations and bind to HLA class I with various avidities

Leukocyte immunoglobulin-like receptor B1 (LILRB1) is widely expressed on various immune cells and the engagement of LILRB1 to HLA class I and pathogen-derived proteins can modulate the immune response. In the current study, 108 LILRB1 alleles were identified by screening the LILRB1 locus from the 1...

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Detalles Bibliográficos
Autores principales: Liu, Fuguo, Cocker, Alexander T. H., Pugh, Jason L., Djaoud, Zakia, Parham, Peter, Guethlein, Lisbeth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9103611/
https://www.ncbi.nlm.nih.gov/pubmed/35562487
http://dx.doi.org/10.1007/s00251-022-01264-7