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Genetic and epigenetic mechanisms influencing acute to chronic postsurgical pain transitions in pediatrics: Preclinical to clinical evidence

BACKGROUND: Chronic postsurgical pain (CPSP) in children remains an important problem with no effective preventive or therapeutic strategies. Recently, genomic underpinnings explaining additional interindividual risk beyond psychological factors have been proposed. AIMS: We present a comprehensive r...

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Detalles Bibliográficos
Autores principales: Dourson, Adam J., Willits, Adam, Raut, Namrata G.R., Kader, Leena, Young, Erin, Jankowski, Michael P., Chidambaran, Vidya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9103644/
https://www.ncbi.nlm.nih.gov/pubmed/35572362
http://dx.doi.org/10.1080/24740527.2021.2021799