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The Cytoskeleton Effectors Rho-Kinase (ROCK) and Mammalian Diaphanous-Related (mDia) Formin Have Dynamic Roles in Tumor Microtube Formation in Invasive Glioblastoma Cells

Glioblastoma (GBM) is a progressive and lethal brain cancer. Malignant control of actin and microtubule cytoskeletal mechanics facilitates two major GBM therapeutic resistance strategies—diffuse invasion and tumor microtube network formation. Actin and microtubule reorganization is controlled by Rho...

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Detalles Bibliográficos
Autores principales: Becker, Kathryn N., Pettee, Krista M., Sugrue, Amanda, Reinard, Kevin A., Schroeder, Jason L., Eisenmann, Kathryn M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9103681/
https://www.ncbi.nlm.nih.gov/pubmed/35563863
http://dx.doi.org/10.3390/cells11091559