New Panx-1 Blockers: Synthesis, Biological Evaluation and Molecular Dynamic Studies

The channel protein Panx-1 is involved in some pathologies, such as epilepsy, ischemic stroke, cancer and Parkinson’s disease, as well as in neuropathic pain. These observations make Panx-1 an interesting biological target. We previously published some potent indole derivatives as Panx-1 blockers, a...

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Detalles Bibliográficos
Autores principales: Crocetti, Letizia, Guerrini, Gabriella, Giovannoni, Maria Paola, Melani, Fabrizio, Lamanna, Silvia, Di Cesare Mannelli, Lorenzo, Lucarini, Elena, Ghelardini, Carla, Wang, Junjie, Dahl, Gerhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9103715/
https://www.ncbi.nlm.nih.gov/pubmed/35563213
http://dx.doi.org/10.3390/ijms23094827

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9103715/
https://www.ncbi.nlm.nih.gov/pubmed/35563213
http://dx.doi.org/10.3390/ijms23094827

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