VI-116, A Novel Potent Inhibitor of VRAC with Minimal Effect on ANO1

Volume-regulated anion channel (VRAC) is ubiquitously expressed and plays a pivotal role in vertebrate cell volume regulation. A heterologous complex of leucine-rich repeat containing 8A (LRRC8A) and LRRC8B-E constitutes the VRAC, which is involved in various processes such as cell proliferation, mi...

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Detalles Bibliográficos
Autores principales: Jeon, Dongkyu, Ryu, Kunhi, Jo, Sungwoo, Kim, Ikyon, Namkung, Wan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9103758/
https://www.ncbi.nlm.nih.gov/pubmed/35563558
http://dx.doi.org/10.3390/ijms23095168

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9103758/
https://www.ncbi.nlm.nih.gov/pubmed/35563558
http://dx.doi.org/10.3390/ijms23095168

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