Cargando…

PRDX2 Knockdown Inhibits Extracellular Matrix Synthesis of Chondrocytes by Inhibiting Wnt5a/YAP1/CTGF and Activating IL-6/JAK2/STAT3 Pathways in Deer Antler

Although peroxiredoxin 2 (PRDX2) plays a vital role in relieving oxidative stress, its physiological function in cartilage development remains almost unknown. In this study, we found that the expression of PRDX2 significantly increased in the chondrocytes compared with pre-chondrocytes. PRDX2 knockd...

Descripción completa

Detalles Bibliográficos
Autores principales: Sun, Xuyang, Gu, Xiaoying, Peng, Jingna, Yang, Liguo, Zhang, Xinxin, Ran, Zaohong, Xiong, Jiajun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9103832/
https://www.ncbi.nlm.nih.gov/pubmed/35563622
http://dx.doi.org/10.3390/ijms23095232