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PRDX2 Knockdown Inhibits Extracellular Matrix Synthesis of Chondrocytes by Inhibiting Wnt5a/YAP1/CTGF and Activating IL-6/JAK2/STAT3 Pathways in Deer Antler
Although peroxiredoxin 2 (PRDX2) plays a vital role in relieving oxidative stress, its physiological function in cartilage development remains almost unknown. In this study, we found that the expression of PRDX2 significantly increased in the chondrocytes compared with pre-chondrocytes. PRDX2 knockd...
Autores principales: | Sun, Xuyang, Gu, Xiaoying, Peng, Jingna, Yang, Liguo, Zhang, Xinxin, Ran, Zaohong, Xiong, Jiajun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9103832/ https://www.ncbi.nlm.nih.gov/pubmed/35563622 http://dx.doi.org/10.3390/ijms23095232 |
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