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Therapeutics Targeting p53-MDM2 Interaction to Induce Cancer Cell Death
Named as the guardian of the genome, p53 is a tumor suppressor that regulates cell function, often through many different mechanisms such as DNA repair, apoptosis, cell cycle arrest, senescence, metabolism, and autophagy. One of the genes that p53 activates is MDM2, which forms a negative feedback l...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9103871/ https://www.ncbi.nlm.nih.gov/pubmed/35563397 http://dx.doi.org/10.3390/ijms23095005 |