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Bacteria-Derived Protein Aggregates Contribute to the Disruption of Host Proteostasis

Neurodegenerative protein conformational diseases are characterized by the misfolding and aggregation of metastable proteins encoded within the host genome. The host is also home to thousands of proteins encoded within exogenous genomes harbored by bacteria, fungi, and viruses. Yet, their contributi...

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Detalles Bibliográficos
Autores principales: Walker, Alyssa C., Bhargava, Rohan, Dove, Autumn S., Brust, Amanda S., Owji, Ali A., Czyż, Daniel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9103901/
https://www.ncbi.nlm.nih.gov/pubmed/35563197
http://dx.doi.org/10.3390/ijms23094807