Bis-Cinnamamide Derivatives as APE/Ref-1 Inhibitors for the Treatment of Human Melanoma

Human malignant melanoma exhibits imbalances in redox status, leading to activation of many redox-sensitive signaling pathways. APE/Ref-1 is a multifunctional protein that serves as a redox chaperone that regulates many nuclear transcription factors and is an important mechanism in cancer cell survi...

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Detalles Bibliográficos
Autores principales: Alhazmi, Razan, Tong, Shirley, Darwish, Shaban, Khanjani, Elina, Khungar, Bharti, Chawla, Swati, Zheng, Zhonghui, Chamberlin, Richard, Parang, Keykavous, Yang, Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9103902/
https://www.ncbi.nlm.nih.gov/pubmed/35566022
http://dx.doi.org/10.3390/molecules27092672

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9103902/
https://www.ncbi.nlm.nih.gov/pubmed/35566022
http://dx.doi.org/10.3390/molecules27092672

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