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Bis-Cinnamamide Derivatives as APE/Ref-1 Inhibitors for the Treatment of Human Melanoma
Human malignant melanoma exhibits imbalances in redox status, leading to activation of many redox-sensitive signaling pathways. APE/Ref-1 is a multifunctional protein that serves as a redox chaperone that regulates many nuclear transcription factors and is an important mechanism in cancer cell survi...
Autores principales: | Alhazmi, Razan, Tong, Shirley, Darwish, Shaban, Khanjani, Elina, Khungar, Bharti, Chawla, Swati, Zheng, Zhonghui, Chamberlin, Richard, Parang, Keykavous, Yang, Sun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9103902/ https://www.ncbi.nlm.nih.gov/pubmed/35566022 http://dx.doi.org/10.3390/molecules27092672 |
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