Cargando…

Dissecting the Genetic and Non-Genetic Heterogeneity of Acute Myeloid Leukemia Using Next-Generation Sequencing and In Vivo Models

SIMPLE SUMMARY: Acute myeloid leukemia (AML) is an extremely aggressive form of blood cancer with high rates of treatment failure. AML arises from the stepwise acquisition of genetic aberrations and is a highly heterogeneous disorder. Recent research has shown that individual AML samples often conta...

Descripción completa

Detalles Bibliográficos
Autores principales:	Desai, Rhea H., Zandvakili, Niloofar, Bohlander, Stefan K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9103951/ https://www.ncbi.nlm.nih.gov/pubmed/35565315 http://dx.doi.org/10.3390/cancers14092182

Ejemplares similares

Comprehensive genetic diagnosis of acute myeloid leukemia by next-generation sequencing
por: Mack, Elisabeth K.M., et al.
Publicado: (2019)

Mixed phenotype acute leukemia contains heterogeneous genetic mutations by next-generation sequencing
por: Quesada, Andrés E., et al.
Publicado: (2018)

Next-generation sequencing-based genetic landscape and its clinical implications for Chinese acute myeloid leukemia patients
por: Cao, Xin-xin, et al.
Publicado: (2018)

Next Generation Sequencing of Acute Myeloid Leukemia: Influencing Prognosis
por: Ilyas, Asad Muhammad, et al.
Publicado: (2015)

Correction to: Next-generation sequencing-based genetic landscape and its clinical implications for Chinese acute myeloid leukemia patients
por: Cao, Xin-xin, et al.
Publicado: (2019)

Characteristics and prognostic significance of genetic mutations in acute myeloid leukemia based on a targeted next‐generation sequencing technique
por: Wang, Rui‐Qi, et al.
Publicado: (2020)

Advancing leukemia diagnostics: Role of Next Generation Sequencing (NGS) in acute myeloid leukemia
por: Haferlach, Torsten
Publicado: (2020)

Genomics of Acute Myeloid Leukemia: The Next Generation
por: Riva, Laura, et al.
Publicado: (2012)

Discovering myeloid cell heterogeneity in the lung by means of next generation sequencing
por: Ji, Jing-jing, et al.
Publicado: (2019)

Next-Generation Sequencing–Based Genomic Profiling of Children with Acute Myeloid Leukemia
por: Krizsán, Szilvia, et al.
Publicado: (2023)

Targeted next generation sequencing of parotid gland cancer uncovers genetic heterogeneity
por: Grünewald, Inga, et al.
Publicado: (2015)

Comprehensive genetic analyses of childhood acute leukemia in Iraq using next-generation sequencing
por: Al-Kzayer, Lika’a Fasih Y., et al.
Publicado: (2023)

Genetic alterations in Thai adult patients with acute myeloid leukemia and myelodysplastic syndrome—excess blasts detected by next-generation sequencing technique
por: Owattanapanich, Weerapat, et al.
Publicado: (2021)

Distinct evolution and dynamics of epigenetic and genetic heterogeneity in acute myeloid leukemia
por: Li, Sheng, et al.
Publicado: (2016)

Next-generation sequencing in the diagnosis and minimal residual disease assessment of acute myeloid leukemia
por: Levine, Ross L., et al.
Publicado: (2019)

Measurable Residual Disease Testing Using Next-Generation Sequencing in Acute Myeloid Leukemia
por: Kim, Seon Young, et al.
Publicado: (2023)

Targeted next-generation sequencing helps to decipher the genetic and phenotypic heterogeneity of hypertrophic cardiomyopathy
por: Cecconi, Massimiliano, et al.
Publicado: (2016)

High Genetic Heterogeneity in Chinese Patients With Waardenburg Syndrome Revealed by Next-Generation Sequencing
por: Zhang, Sen, et al.
Publicado: (2021)

Genetic, Phenotypic, and Clinical Heterogeneity of NPM1-Mutant Acute Myeloid Leukemias
por: Testa, Ugo, et al.
Publicado: (2023)

Next-generation dendritic cells for immunotherapy of acute myeloid leukemia
por: Schnorfeil, Frauke, et al.
Publicado: (2014)

Experiences with Next-Generation Sequencing in Relapsed Acute Myeloid Leukemia: A Patient Case Series
por: Flach, Johanna, et al.
Publicado: (2020)

Biomarkers in Acute Myeloid Leukemia: Leveraging Next Generation Sequencing Data for Optimal Therapeutic Strategies
por: El Achi, Hanadi, et al.
Publicado: (2021)

Validation and refinement of the revised 2017 European LeukemiaNet genetic risk stratification of acute myeloid leukemia
por: Herold, Tobias, et al.
Publicado: (2020)

Next-Generation Sequencing in Acute Lymphoblastic Leukemia
por: Coccaro, Nicoletta, et al.
Publicado: (2019)

Identification of Prognostic and Susceptibility Markers in Chronic Myeloid Leukemia Using Next Generation Sequencing
por: Shokeen, Yogender, et al.
Publicado: (2018)

Detection of minimal residual disease in NPM1-mutated acute myeloid leukemia by next-generation sequencing
por: Salipante, Stephen J., et al.
Publicado: (2014)

Panel-based next-generation sequencing facilitates the characterization of childhood acute myeloid leukemia in clinical settings
por: Ishida, Hisashi, et al.
Publicado: (2020)

Transforming Acute Myeloid Leukemia Treatment Through Next-Generation Sequencing: A Single-Center Experience
por: Devarkonda, Vishal, et al.
Publicado: (2023)

Impact of Next-Generation Sequencing in Diagnosis, Prognosis and Therapeutic Management of Acute Myeloid Leukemia/Myelodysplastic Neoplasms
por: Madaci, Lamia, et al.
Publicado: (2023)

Next generation genetics
por: Fenger, Mogens
Publicado: (2014)

New genetic variants of TET2 and ASXL1 identified by next generation sequencing and pyrosequencing in a patient with MDS-RS-MLD and secondary acute myeloid leukemia
por: Adamska, Monika Małgorzata, et al.
Publicado: (2021)

Clonal heterogeneity of FLT3-ITD detected by high-throughput amplicon sequencing correlates with adverse prognosis in acute myeloid leukemia
por: Schranz, Katrin, et al.
Publicado: (2018)

Principles of Genetic Counseling in the Era of Next-Generation Sequencing
por: Yang, Mina, et al.
Publicado: (2018)

Dissecting the genetic heterogeneity of gastric cancer
por: Hess, Timo, et al.
Publicado: (2023)

Concomitant ATM Mutations Identified by Next Generation Sequencing in a Patient With New-Onset Acute Myeloid Leukemia Following Imatinib Treatment for Chronic Myeloid Leukemia
por: Stein, Matthew K., et al.
Publicado: (2018)

Serial Analysis and Comparison of Mutation Profiles in Decitabine-treated Myeloid Sarcoma and Subsequent Acute Myeloid Leukemia Using Next-Generation Sequencing
por: Park, Hee Sue, et al.
Publicado: (2022)

Mutational spectrum and risk stratification of intermediate-risk acute myeloid leukemia patients based on next-generation sequencing
por: Wang, Bianhong, et al.
Publicado: (2016)

Delineation of Molecular Lesions in Acute Myeloid Leukemia Patients at Diagnosis: Integrated Next Generation Sequencing and Cytogenomic Studies
por: Papuc, Sorina Mihaela, et al.
Publicado: (2021)

Next-Generation Sequencing Revealed a Distinct Immunoglobulin Repertoire with Specific Mutation Hotspots in Acute Myeloid Leukemia
por: Xia, Miaoran, et al.
Publicado: (2022)

FLT3-ITD Measurable Residual Disease Monitoring in Acute Myeloid Leukemia Using Next-Generation Sequencing
por: Lee, Jong-Mi, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_ov9btpltt54i8lsid2kaepd66g