Dissecting the Genetic and Non-Genetic Heterogeneity of Acute Myeloid Leukemia Using Next-Generation Sequencing and In Vivo Models

SIMPLE SUMMARY: Acute myeloid leukemia (AML) is an extremely aggressive form of blood cancer with high rates of treatment failure. AML arises from the stepwise acquisition of genetic aberrations and is a highly heterogeneous disorder. Recent research has shown that individual AML samples often conta...

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Detalles Bibliográficos
Autores principales: Desai, Rhea H., Zandvakili, Niloofar, Bohlander, Stefan K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9103951/
https://www.ncbi.nlm.nih.gov/pubmed/35565315
http://dx.doi.org/10.3390/cancers14092182