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PI3K Inhibitors in Advanced Breast Cancer: The Past, The Present, New Challenges and Future Perspectives

SIMPLE SUMMARY: Molecular aberrations in the phosphatidylinositol 3-kinase (PI3K) pathway are often observed in breast cancer and represent a key regulator of many cellular processes, promoting tumor cell growth and survival. The first clinical trials leading to the development of pan-PI3K inhibitor...

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Detalles Bibliográficos
Autores principales: Fuso, Paola, Muratore, Margherita, D’Angelo, Tatiana, Paris, Ida, Carbognin, Luisa, Tiberi, Giordana, Pavese, Francesco, Duranti, Simona, Orlandi, Armando, Tortora, Giampaolo, Scambia, Giovanni, Fabi, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9103982/
https://www.ncbi.nlm.nih.gov/pubmed/35565291
http://dx.doi.org/10.3390/cancers14092161