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IL-6 Responsiveness of CD4(+) and CD8(+) T Cells after Allogeneic Stem Cell Transplantation Differs between Patients and Is Associated with Previous Acute Graft versus Host Disease and Pretransplant Antithymocyte Globulin Therapy

Graft-versus-host disease (GVHD), one of the most common and serious complications after allogeneic stem cell transplantation, is mediated by allocative T cells. IL-6 mediates both pro- and anti-inflammatory effects and modulates T cell response through classical signaling and trans-signaling. We in...

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Detalles Bibliográficos
Autores principales: Tvedt, Tor Henrik Anderson, Rose-John, Stefan, Tsykunova, Galina, Ahmed, Aymen Bushra, Gedde-Dahl, Tobias, Ersvær, Elisabeth, Bruserud, Øystein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9104003/
https://www.ncbi.nlm.nih.gov/pubmed/35566660
http://dx.doi.org/10.3390/jcm11092530