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Role of Polyamine-Induced Dimerization of Antizyme in Its Cellular Functions

The polyamines, spermine (Spm) and spermidine (Spd), are important for cell growth and function. Their homeostasis is strictly controlled, and a key downregulator of the polyamine pool is the polyamine-inducible protein, antizyme 1 (OAZ1). OAZ1 inhibits polyamine uptake and targets ornithine decarbo...

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Detalles Bibliográficos
Autores principales: Hyvönen, Mervi T., Smirnova, Olga A., Mitkevich, Vladimir A., Tunitskaya, Vera L., Khomutov, Maxim, Karpov, Dmitry S., Korolev, Sergey P., Häkkinen, Merja R., Pietilä, Marko, Gottikh, Marina B., Vepsäläinen, Jouko, Alhonen, Leena, Makarov, Alexander A., Kochetkov, Sergey N., Wallace, Heather M., Keinänen, Tuomo A., Khomutov, Alex R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9104013/
https://www.ncbi.nlm.nih.gov/pubmed/35563006
http://dx.doi.org/10.3390/ijms23094614