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Oncogenic Kras-Mediated Cytokine CCL15 Regulates Pancreatic Cancer Cell Migration and Invasion through ROS

SIMPLE SUMMARY: Oncogenic Kras(G12D) and tumor inflammation are critical components of the development and dissemination of pancreatic ductal adenocarcinoma (PDAC). The aim of this study is to investigate a lesser-known cytokine, CCL15, that functions as a new downstream target of Kras(G12D) with th...

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Detalles Bibliográficos
Autores principales: Messex, Justin K., Adams, Kiyah L. A., Hawkins, William G., DeNardo, David, Bardeesy, Nabeel, Billadeau, Daniel D., Liou, Geou-Yarh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9104113/
https://www.ncbi.nlm.nih.gov/pubmed/35565279
http://dx.doi.org/10.3390/cancers14092153