Toward the Discovery of a Novel Class of Leads for High Altitude Disorders by Virtual Screening and Molecular Dynamics Approaches Targeting Carbonic Anhydrase

For decades, carbonic anhydrase (CA) inhibitors, most notably the acetazolamide-bearing 1,3,4-thiadiazole moiety, have been exploited at high altitudes to alleviate acute mountain sickness, a syndrome of symptomatic sensitivity to the altitude characterized by nausea, lethargy, headache, anorexia, a...

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Detalles Bibliográficos
Autores principales: Ali, Amena, Ali, Abuzer, Warsi, Musarrat Husain, Rahman, Mohammad Akhlaquer, Ahsan, Mohamed Jawed, Azam, Faizul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9104310/
https://www.ncbi.nlm.nih.gov/pubmed/35563445
http://dx.doi.org/10.3390/ijms23095054

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9104310/
https://www.ncbi.nlm.nih.gov/pubmed/35563445
http://dx.doi.org/10.3390/ijms23095054

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