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Nano-Sized Extracellular Vesicles Secreted from GATA-4 Modified Mesenchymal Stem Cells Promote Angiogenesis by Delivering Let-7 miRNAs

We demonstrated previously that extracellular vesicles (EVs) released from mesenchymal stem cells (MSCs) play a critical role in angiogenesis. Here, we examine whether this pro-angiogenic efficacy is enhanced in EVs derived from MSCs overexpressing GATA-4 (MSC(GATA−4)). Methods and Results. EVs were...

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Detalles Bibliográficos
Autores principales: Gong, Min, Wang, Min, Xu, Jie, Yu, Bin, Wang, Yi-Gang, Liu, Min, Ashraf, Muhammad, Xu, Meifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9104414/
https://www.ncbi.nlm.nih.gov/pubmed/35563879
http://dx.doi.org/10.3390/cells11091573