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Sequencing of the Viral UL111a Gene Directly from Clinical Specimens Reveals Variants of HCMV-Encoded IL-10 That Are Associated with Altered Immune Responses to HCMV

Human cytomegalovirus (HCMV) is a beta-herpesvirus carried by ~80% of adults worldwide. Acute infections are often asymptomatic in healthy individuals but generate diverse syndromes in neonates, renal transplant recipients (RTR), and people with HIV (PWH). The HCMV gene UL111a encodes a homolog of h...

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Detalles Bibliográficos
Autores principales: Waters, Shelley, Lee, Silvia, Ariyanto, Ibnu, Kresoje, Nina, Leary, Shay, Munyard, Kylie, Gaudieri, Silvana, Irish, Ashley, Keil, Anthony D., Allcock, Richard J. N., Price, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9104433/
https://www.ncbi.nlm.nih.gov/pubmed/35563032
http://dx.doi.org/10.3390/ijms23094644