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Cocaprins, β-Trefoil Fold Inhibitors of Cysteine and Aspartic Proteases from Coprinopsis cinerea

We introduce a new family of fungal protease inhibitors with β-trefoil fold from the mushroom Coprinopsis cinerea, named cocaprins, which inhibit both cysteine and aspartic proteases. Two cocaprin-encoding genes are differentially expressed in fungal tissues. One is highly transcribed in vegetative...

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Detalles Bibliográficos
Autores principales: Renko, Miha, Zupan, Tanja, Plaza, David F., Schmieder, Stefanie S., Perišić Nanut, Milica, Kos, Janko, Turk, Dušan, Künzler, Markus, Sabotič, Jerica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9104457/
https://www.ncbi.nlm.nih.gov/pubmed/35563308
http://dx.doi.org/10.3390/ijms23094916