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Nutraceuticals/Drugs Promoting Mitophagy and Mitochondrial Biogenesis May Combat the Mitochondrial Dysfunction Driving Progression of Dry Age-Related Macular Degeneration

In patients with age-related macular degeneration (AMD), the crucial retinal pigment epithelial (RPE) cells are characterized by mitochondria that are structurally and functionally defective. Moreover, deficient expression of the mRNA-editing enzyme Dicer is noted specifically in these cells. This D...

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Detalles Bibliográficos
Autores principales: Lewis Luján, Lidianys María, McCarty, Mark F., Di Nicolantonio, James J., Gálvez Ruiz, Juan Carlos, Rosas-Burgos, Ema Carina, Plascencia-Jatomea, Maribel, Iloki Assanga, Simon Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9104458/
https://www.ncbi.nlm.nih.gov/pubmed/35565950
http://dx.doi.org/10.3390/nu14091985