Bioavailability Enhancement of Cepharanthine via Pulmonary Administration in Rats and Its Therapeutic Potential for Pulmonary Fibrosis Associated with COVID-19 Infection

Cepharanthine (CEP) has excellent anti-SARS-CoV-2 properties, indicating its favorable potential for COVID-19 treatment. However, its application is challenged by its poor dissolubility and oral bioavailability. The present study aimed to improve the bioavailability of CEP by optimizing its solubili...

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Detalles Bibliográficos
Autores principales: Li, Jian, Chen, Guangrui, Meng, Zhiyun, Wu, Zhuona, Gan, Hui, Zhu, Xiaoxia, Han, Peng, Liu, Taoyun, Wang, Fanjun, Gu, Ruolan, Dou, Guifang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9104485/
https://www.ncbi.nlm.nih.gov/pubmed/35566097
http://dx.doi.org/10.3390/molecules27092745

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9104485/
https://www.ncbi.nlm.nih.gov/pubmed/35566097
http://dx.doi.org/10.3390/molecules27092745

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