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Antigen Cross-Presentation by Murine Proximal Tubular Epithelial Cells Induces Cytotoxic and Inflammatory CD8(+) T Cells

Immune-mediated glomerular diseases are characterized by infiltration of T cells, which accumulate in the periglomerular space and tubulointerstitium in close contact to proximal and distal tubuli. Recent studies described proximal tubular epithelial cells (PTECs) as renal non-professional antigen-p...

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Detalles Bibliográficos
Autores principales: Linke, Alexandra, Cicek, Hakan, Müller, Anne, Meyer-Schwesinger, Catherine, Melderis, Simon, Wiech, Thorsten, Wegscheid, Claudia, Ridder, Julius, Steinmetz, Oliver M., Diehl, Linda, Tiegs, Gisa, Neumann, Katrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9104549/
https://www.ncbi.nlm.nih.gov/pubmed/35563816
http://dx.doi.org/10.3390/cells11091510