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Direct Detection of Glutathione Biosynthesis, Conjugation, Depletion and Recovery in Intact Hepatoma Cells
Nuclear magnetic resonance (NMR) spectroscopy was used to monitor glutathione metabolism in alginate-encapsulated JM-1 hepatoma cells perfused with growth media containing [3,3′-(13)C(2)]-cystine. After 20 h of perfusion with labeled medium, the (13)C NMR spectrum is dominated by the signal from the...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9104575/ https://www.ncbi.nlm.nih.gov/pubmed/35563124 http://dx.doi.org/10.3390/ijms23094733 |