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The Effects of Taurocholic Acid on Biliary Damage and Liver Fibrosis Are Mediated by Calcitonin-Gene-Related Peptide Signaling

Background & aims: Cholangiocytes are the target cells of liver diseases that are characterized by biliary senescence (evidenced by enhanced levels of senescence-associated secretory phenotype, SASP, e.g., TGF-β1), and liver inflammation and fibrosis accompanied by altered bile acid (BA) homeost...

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Detalles Bibliográficos
Autores principales: Mancinelli, Romina, Ceci, Ludovica, Kennedy, Lindsey, Francis, Heather, Meadows, Vik, Chen, Lixian, Carpino, Guido, Kyritsi, Konstantina, Wu, Nan, Zhou, Tianhao, Sato, Keisaku, Pannarale, Luigi, Glaser, Shannon, Chakraborty, Sanjukta, Alpini, Gianfranco, Gaudio, Eugenio, Onori, Paolo, Franchitto, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9104610/
https://www.ncbi.nlm.nih.gov/pubmed/35563897
http://dx.doi.org/10.3390/cells11091591