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Oncostatin M Induces Lipolysis and Suppresses Insulin Response in 3T3-L1 Adipocytes

Oncostatin M (OSM) is an immune cell-derived cytokine that is upregulated in adipose tissue in obesity. Upon binding its receptor (OSMR), OSM induces the phosphorylation of the p66 subunit of Src homology 2 domain-containing transforming protein 1 (SHC1), called p66Shc, and activates the extracellul...

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Detalles Bibliográficos
Autores principales: Bailey, Jennifer L., Hang, Hardy, Boudreau, Anik, Elks, Carrie M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9104719/
https://www.ncbi.nlm.nih.gov/pubmed/35563078
http://dx.doi.org/10.3390/ijms23094689