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The Anti-Atherosclerosis Effect of Anakinra, a Recombinant Human Interleukin-1 Receptor Antagonist, in Apolipoprotein E Knockout Mice

Interleukin (IL)-1β plays an important role in atherosclerosis pathogenesis. We aimed to investigate the effect of anakinra, a recombinant human IL-1 receptor antagonist, on the progression of atherosclerosis in apolipoprotein E knockout (ApoE(–/–)) mice. ApoE(–/–) mice (8-week male) were treated wi...

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Detalles Bibliográficos
Autores principales: Ku, Eu Jeong, Kim, Bo-Rahm, Lee, Jee-In, Lee, Yun Kyung, Oh, Tae Jung, Jang, Hak C., Choi, Sung Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9104865/
https://www.ncbi.nlm.nih.gov/pubmed/35563294
http://dx.doi.org/10.3390/ijms23094906