Disulfiram Exerts Antifibrotic and Anti-Inflammatory Therapeutic Effects on Perimysial Orbital Fibroblasts in Graves’ Orbitopathy

Fibrosis of extraocular muscles (EOMs) is a marker of end-stage in Graves’ orbitopathy (GO). To determine the antifibrotic and anti-inflammatory therapeutic effects and the underlying molecular mechanisms of disulfiram (DSF) on perimysial orbital fibroblasts (pOFs) in a GO model in vitro, primary cu...

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Detalles Bibliográficos
Autores principales: Wang, Xing, Ye, Huijing, Yang, Shenglan, Sha, Xiaotong, Wang, Xiandai, Zhang, Te, Chen, Rongxin, Xiao, Wei, Yang, Huasheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9104881/
https://www.ncbi.nlm.nih.gov/pubmed/35563653
http://dx.doi.org/10.3390/ijms23095261

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9104881/
https://www.ncbi.nlm.nih.gov/pubmed/35563653
http://dx.doi.org/10.3390/ijms23095261

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