Zileuton, a 5-Lipoxygenase Inhibitor, Attenuates Haemolysate-Induced BV-2 Cell Activation by Suppressing the MyD88/NF-κB Pathway

M1 microglia induce neuroinflammation-related neuronal death in animal models of spontaneous subarachnoid haemorrhage. Zileuton is a 5-lipoxygenase inhibitor that reduces the levels of downstream pro-inflammatory cytokines. This study aimed to investigate whether zileuton inhibits microglial activat...

Descripción completa

Detalles Bibliográficos
Autores principales: Su, Hui-Yuan, Tsai, Yi-Cheng, Tsai, Hung-Pei, Lin, Chih-Lung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9104905/
https://www.ncbi.nlm.nih.gov/pubmed/35563304
http://dx.doi.org/10.3390/ijms23094910

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9104905/
https://www.ncbi.nlm.nih.gov/pubmed/35563304
http://dx.doi.org/10.3390/ijms23094910

Ejemplares similares