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Quantification and Improvement of the Dynamics of Human Serum Albumin and Glycated Human Serum Albumin with Astaxanthin/Astaxanthin-Metal Ion Complexes: Physico-Chemical and Computational Approaches

Glycated human serum albumin (gHSA) undergoes conformational changes and unfolding events caused by free radicals. The glycation process results in a reduced ability of albumin to act as an endogenous scavenger and transporter protein in diabetes mellitus type 2 (T2DM) patients. Astaxanthin (ASX) in...

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Detalles Bibliográficos
Autores principales: Wibowo, Syahputra, Costa, Jessica, Baratto, Maria Camilla, Pogni, Rebecca, Widyarti, Sri, Sabarudin, Akhmad, Matsuo, Koichi, Sumitro, Sutiman Bambang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9104927/
https://www.ncbi.nlm.nih.gov/pubmed/35563162
http://dx.doi.org/10.3390/ijms23094771