Combined Treatment with PI3K Inhibitors BYL-719 and CAL-101 Is a Promising Antiproliferative Strategy in Human Rhabdomyosarcoma Cells

Rhabdomyosarcoma (RMS) is a highly malignant and metastatic pediatric cancer arising from skeletal muscle myogenic progenitors. Recent studies have shown an important role for AKT signaling in RMS progression. Aberrant activation of the PI3K/AKT axis is one of the most frequent events occurring in h...

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Detalles Bibliográficos
Autores principales: Piazzi, Manuela, Bavelloni, Alberto, Cenni, Vittoria, Salucci, Sara, Bartoletti Stella, Anna, Tomassini, Enrica, Scotlandi, Katia, Blalock, William L., Faenza, Irene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9104989/
https://www.ncbi.nlm.nih.gov/pubmed/35566091
http://dx.doi.org/10.3390/molecules27092742

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9104989/
https://www.ncbi.nlm.nih.gov/pubmed/35566091
http://dx.doi.org/10.3390/molecules27092742

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