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Urine-Derived Stem Cell-Secreted Klotho Plays a Crucial Role in the HK-2 Fibrosis Model by Inhibiting the TGF-β Signaling Pathway
Renal fibrosis is an irreversible and progressive process that causes severe dysfunction in chronic kidney disease (CKD). The progression of CKD stages is highly associated with a gradual reduction in serum Klotho levels. We focused on Klotho protein as a key therapeutic factor against CKD. Urine-de...
Autores principales: | Kim, Sang-Heon, Jin, Jeong-Ah, So, Hyung Joon, Lee, Sung Hoon, Kang, Tae-Wook, Lee, Jae-Ung, Choi, Dae Eun, Jeong, Jin Young, Chang, Yoon-Kyung, Choi, Hyunsu, Lee, Youngjun, Seo, Young-Kwon, Lee, Hong-Ki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9105028/ https://www.ncbi.nlm.nih.gov/pubmed/35563402 http://dx.doi.org/10.3390/ijms23095012 |
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