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Plasma-Based Measurements of Tumor Heterogeneity Correlate with Clinical Outcomes in Metastatic Colorectal Cancer

SIMPLE SUMMARY: Molecular characterization of circulating tumor DNA (ctDNA) can offer a window into tumor genetic heterogeneity, especially in metastatic cancers where different lesions may harbor different mutations. The presence of multiple tumor clones may be reflected by dispersed variant allele...

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Detalles Bibliográficos
Autores principales: Yaung, Stephanie J., Ju, Christine, Gattam, Sandeep, Nicholas, Alan, Sommer, Nicolas, Bendell, Johanna C., Hurwitz, Herbert I., Lee, John J., Casey, Fergal, Price, Richard, Palma, John F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9105064/
https://www.ncbi.nlm.nih.gov/pubmed/35565368
http://dx.doi.org/10.3390/cancers14092240