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Urocortin-1 Is Chondroprotective in Response to Acute Cartilage Injury via Modulation of Piezo1

Post-traumatic OA (PTOA) is often triggered by injurious, high-impact loading events which result in rapid, excessive chondrocyte cell death and a phenotypic shift in residual cells toward a more catabolic state. As such, the identification of a disease-modifying OA drug (DMOAD) that can protect cho...

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Detalles Bibliográficos
Autores principales: Jones, Rebecca C., Lawrence, Kevin M., Higgins, Scott M., Richardson, Stephen M., Townsend, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9105101/
https://www.ncbi.nlm.nih.gov/pubmed/35563508
http://dx.doi.org/10.3390/ijms23095119