Cargando…
Urocortin-1 Is Chondroprotective in Response to Acute Cartilage Injury via Modulation of Piezo1
Post-traumatic OA (PTOA) is often triggered by injurious, high-impact loading events which result in rapid, excessive chondrocyte cell death and a phenotypic shift in residual cells toward a more catabolic state. As such, the identification of a disease-modifying OA drug (DMOAD) that can protect cho...
Autores principales: | Jones, Rebecca C., Lawrence, Kevin M., Higgins, Scott M., Richardson, Stephen M., Townsend, Paul A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9105101/ https://www.ncbi.nlm.nih.gov/pubmed/35563508 http://dx.doi.org/10.3390/ijms23095119 |
Ejemplares similares
-
Chondroprotection by urocortin involves blockade of the mechanosensitive ion channel Piezo1
por: Lawrence, K. M., et al.
Publicado: (2017) -
Chondroprotection in Models of Cartilage Injury by Raising the Temperature and Osmolarity of Irrigation Solutions
por: Eltawil, Noha M., et al.
Publicado: (2017) -
New targets of urocortin-mediated cardioprotection
por: Barry, Seán P, et al.
Publicado: (2010) -
Urocortin suppresses endometrial cancer cell migration via CRFR2 and its system components are differentially modulated by estrogen
por: Owens, Gemma L., et al.
Publicado: (2017) -
Exploring the Role of Urocortin in Osteoporosis
por: Ismail, Omar M, et al.
Publicado: (2023)