Cargando…

Development and Biochemical Characterization of Self-Immolative Linker Containing GnRH-III-Drug Conjugates

The human gonadotropin releasing hormone (GnRH-I) and its sea lamprey analogue GnRH-III specifically bind to GnRH receptors on cancer cells and can be used as targeting moieties for targeted tumor therapy. Considering that the selective release of drugs in cancer cells is of high relevance, we were...

Descripción completa

Detalles Bibliográficos
Autores principales: Schuster, Sabine, Juhász, Éva, Halmos, Gábor, Neundorf, Ines, Gennari, Cesare, Mező, Gábor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9105102/
https://www.ncbi.nlm.nih.gov/pubmed/35563462
http://dx.doi.org/10.3390/ijms23095071