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Development and Biochemical Characterization of Self-Immolative Linker Containing GnRH-III-Drug Conjugates
The human gonadotropin releasing hormone (GnRH-I) and its sea lamprey analogue GnRH-III specifically bind to GnRH receptors on cancer cells and can be used as targeting moieties for targeted tumor therapy. Considering that the selective release of drugs in cancer cells is of high relevance, we were...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9105102/ https://www.ncbi.nlm.nih.gov/pubmed/35563462 http://dx.doi.org/10.3390/ijms23095071 |