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Allopregnanolone Promotes Migration and Invasion of Human Glioblastoma Cells through the Protein Tyrosine Kinase c-Src Activation

Glioblastomas (GBs) are the most aggressive and common primary malignant brain tumors. Steroid hormone progesterone (P4) and its neuroactive metabolites, such as allopregnanolone (3α-THP) are synthesized by neural, glial, and malignant GB cells. P4 promotes cellular proliferation, migration, and inv...

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Detalles Bibliográficos
Autores principales: Zamora-Sánchez, Carmen J., Bello-Alvarez, Claudia, Rodríguez-Dorantes, Mauricio, Camacho-Arroyo, Ignacio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9105169/
https://www.ncbi.nlm.nih.gov/pubmed/35563388
http://dx.doi.org/10.3390/ijms23094996