The Interaction of Anti-DNA Antibodies with DNA: Evidence for Unconventional Binding Mechanisms

Antibodies to DNA (anti-DNA) are the serological hallmark of systemic lupus erythematosus, a prototypic autoimmune disease. These antibodies bind to conserved sites on single-stranded and double-stranded DNA and display variable region somatic mutations consistent with antigen selection. Nevertheles...

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Detalles Bibliográficos
Autores principales: Pisetsky, David S., Garza Reyna, Angel, Belina, Morgan E., Spencer, Diane M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9105193/
https://www.ncbi.nlm.nih.gov/pubmed/35563617
http://dx.doi.org/10.3390/ijms23095227

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9105193/
https://www.ncbi.nlm.nih.gov/pubmed/35563617
http://dx.doi.org/10.3390/ijms23095227

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