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The Interaction of Anti-DNA Antibodies with DNA: Evidence for Unconventional Binding Mechanisms
Antibodies to DNA (anti-DNA) are the serological hallmark of systemic lupus erythematosus, a prototypic autoimmune disease. These antibodies bind to conserved sites on single-stranded and double-stranded DNA and display variable region somatic mutations consistent with antigen selection. Nevertheles...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9105193/ https://www.ncbi.nlm.nih.gov/pubmed/35563617 http://dx.doi.org/10.3390/ijms23095227 |