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BRAF Modulates Lipid Use and Accumulation

SIMPLE SUMMARY: BRAF is a serine/threonine kinase that is commonly mutated across cancers. The BRAF V600E mutation is targetable with kinase inhibitors; however, many patients eventually develop resistance. Recent evidence suggests that tumors harboring BRAF mutations may oxidize fatty acids for ene...

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Detalles Bibliográficos
Autores principales: Turner, Jacqueline A., Paton, Emily L., Van Gulick, Robert, Stefanoni, Davide, Cendali, Francesca, Reisz, Julie, Tobin, Richard P., McCarter, Martin, D’Alessandro, Angelo, Torres, Raul M., Robinson, William A., Couts, Kasey L., Schlaepfer, Isabel R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9105200/
https://www.ncbi.nlm.nih.gov/pubmed/35565240
http://dx.doi.org/10.3390/cancers14092110