Cargando…

Hippocampal Excitatory Synaptic Transmission and Plasticity Are Differentially Altered during Postnatal Development by Loss of the X-Linked Intellectual Disability Protein Oligophrenin-1

Oligophrenin-1 (OPHN1) is a Rho-GTPase-activating protein (RhoGAP), whose mutations are associated with X-linked intellectual disability (XLID). OPHN1 is enriched at the synapse in both pre- and postsynaptic compartments, where it regulates the RhoA/ROCK/MLC2 signaling pathway, playing a critical ro...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cresto, Noemie, Lebrun, Nicolas, Dumont, Florent, Letourneur, Franck, Billuart, Pierre, Rouach, Nathalie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9105236/ https://www.ncbi.nlm.nih.gov/pubmed/35563851 http://dx.doi.org/10.3390/cells11091545

Ejemplares similares

Inhibition of RhoA pathway rescues the endocytosis defects in Oligophrenin1 mouse model of mental retardation
por: Khelfaoui, Malik, et al.
Publicado: (2009)

LGI1 acts presynaptically to regulate excitatory synaptic transmission during early postnatal development
por: Boillot, Morgane, et al.
Publicado: (2016)

Deficiency of Intellectual Disability-Related Gene Brpf1 Attenuated Hippocampal Excitatory Synaptic Transmission and Impaired Spatial Learning and Memory Ability
por: Xian, Weiwei, et al.
Publicado: (2021)

Oligophrenin-1 (OPHN1), a Gene Involved in X-Linked Intellectual Disability, Undergoes RNA Editing and Alternative Splicing during Human Brain Development
por: Barresi, Sabina, et al.
Publicado: (2014)

Plasticity of Hippocampal Excitatory-Inhibitory Balance: Missing the Synaptic Control in the Epileptic Brain
por: Bonansco, Christian, et al.
Publicado: (2016)

Pharmacological rescue of adult hippocampal neurogenesis in a mouse model of X-linked intellectual disability
por: Allegra, Manuela, et al.
Publicado: (2017)

Stimulation of protein synthesis by optogenetic and chemical induction of excitatory synaptic plasticity in hippocampal somatostatin interneurons
por: Honoré, Ève, et al.
Publicado: (2022)

Neddylation regulates excitatory synaptic transmission and plasticity
por: Brockmann, Marisa M., et al.
Publicado: (2019)

Inhibition of Rac1 in ventral hippocampal excitatory neurons improves social recognition memory and synaptic plasticity
por: Zhang, Haiwang, et al.
Publicado: (2022)

Excitatory to inhibitory connectivity shaped by synaptic and homeostatic plasticity
por: Clopath, Claudia, et al.
Publicado: (2015)

Dopamine Modulates Homeostatic Excitatory Synaptic Plasticity of Immature Dentate Granule Cells in Entorhino-Hippocampal Slice Cultures
por: Strehl, Andreas, et al.
Publicado: (2018)

Postnatal activation of TLR4 in astrocytes promotes excitatory synaptogenesis in hippocampal neurons
por: Shen, Yi, et al.
Publicado: (2016)

STK24 modulates excitatory synaptic transmission in epileptic hippocampal neurons
por: Yang, Juan, et al.
Publicado: (2020)

Lifelong changes of neurotransmitter receptor expression and debilitation of hippocampal synaptic plasticity following early postnatal blindness
por: Hagena, Hardy, et al.
Publicado: (2022)

Overexpression of LIMK1 in hippocampal excitatory neurons improves synaptic plasticity and social recognition memory in APP/PS1 mice
por: Zhang, Haiwang, et al.
Publicado: (2021)

Hippocampal Feedforward Inhibition Focuses Excitatory Synaptic Signals into Distinct Dendritic Compartments
por: Willadt, Silvia, et al.
Publicado: (2013)

Synaptic Effects of Munc18-1 Alternative Splicing in Excitatory Hippocampal Neurons
por: Meijer, Marieke, et al.
Publicado: (2015)

Spatial regulation of coordinated excitatory and inhibitory synaptic plasticity at dendritic synapses
por: Ravasenga, Tiziana, et al.
Publicado: (2022)

Upregulation of astroglial connexin 30 impairs hippocampal synaptic activity and recognition memory
por: Hardy, Eléonore, et al.
Publicado: (2023)

Dual Electrophysiological Recordings of Synaptically-evoked Astroglial and Neuronal Responses in Acute Hippocampal Slices
por: Pannasch, Ulrike, et al.
Publicado: (2012)

Metformin Enhances Excitatory Synaptic Transmission onto Hippocampal CA1 Pyramidal Neurons
por: Chen, Wen-Bing, et al.
Publicado: (2020)

TRPC1 mediates slow excitatory synaptic transmission in hippocampal oriens/alveus interneurons
por: Kougioumoutzakis, André, et al.
Publicado: (2020)

Unsupervised discrimination of patterns in spiking neural networks with excitatory and inhibitory synaptic plasticity
por: Srinivasa, Narayan, et al.
Publicado: (2014)

Neuronal megalin mediates synaptic plasticity—a novel mechanism underlying intellectual disabilities in megalin gene pathologies
por: Gomes, João R, et al.
Publicado: (2020)

Ptchd1 deficiency induces excitatory synaptic and cognitive dysfunctions in mouse
por: Ung, D C, et al.
Publicado: (2018)

Impaired Hippocampal Synaptic Plasticity and Enhanced Excitatory Transmission in a Novel Animal Model of Autism Spectrum Disorders with Telomerase Reverse Transcriptase Overexpression
por: Rhee, Jeehae, et al.
Publicado: (2018)

Neuromodulation of hippocampal long-term synaptic plasticity
por: Palacios-Filardo, Jon, et al.
Publicado: (2019)

Age-dependent regulation of excitatory synaptic transmission at hippocampal temporoammonic-CA1 synapses by leptin
por: McGregor, Gemma, et al.
Publicado: (2018)

Different priming states of synaptic vesicles underlie distinct release probabilities at hippocampal excitatory synapses
por: Aldahabi, Mohammad, et al.
Publicado: (2022)

From Abnormal Hippocampal Synaptic Plasticity in Down Syndrome Mouse Models to Cognitive Disability in Down Syndrome
por: Cramer, Nathan, et al.
Publicado: (2012)

Glucose Rapidly Induces Different Forms of Excitatory Synaptic Plasticity in Hypothalamic POMC Neurons
por: Hu, Jun, et al.
Publicado: (2014)

Domestication of the Dog from the Wolf Was Promoted by Enhanced Excitatory Synaptic Plasticity: A Hypothesis
por: Li, Yan, et al.
Publicado: (2014)

Astroglial calcium signaling displays short-term plasticity and adjusts synaptic efficacy
por: Sibille, Jérémie, et al.
Publicado: (2015)

The X-Linked Intellectual Disability Protein TSPAN7 Regulates Excitatory Synapse Development and AMPAR Trafficking
por: Bassani, Silvia, et al.
Publicado: (2012)

Astroglial Connexin 43 Regulates Synaptic Vesicle Release at Hippocampal Synapses
por: Cheung, Giselle, et al.
Publicado: (2023)

Gestational dexamethasone exposure impacts hippocampal excitatory synaptic transmission and learning and memory function with transgenerational effects
por: Luo, Mingcui, et al.
Publicado: (2023)

A TrkB agonist and ampakine rescue synaptic plasticity and multiple forms of memory in a mouse model of intellectual disability
por: Seese, Ronald R., et al.
Publicado: (2019)

The requirement of BDNF for hippocampal synaptic plasticity is experience‐dependent
por: Aarse, Janna, et al.
Publicado: (2016)

Bidirectional synaptic plasticity rapidly modifies hippocampal representations
por: Milstein, Aaron D, et al.
Publicado: (2021)

Excitatory synaptic dysfunction cell-autonomously decreases inhibitory inputs and disrupts structural and functional plasticity
por: He, Hai-yan, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_rulj2vvq7j2sg8qdao5jjmgajo