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CXCR4/CXCL12 Activities in the Tumor Microenvironment and Implications for Tumor Immunotherapy
SIMPLE SUMMARY: Chemokines are small soluble proteins that control and regulate cell trafficking within and between tissues by binding to their receptors. Among them, CXCL12 and its receptor CXCR4 appeared with ancestral vertebrates, are expressed almost ubiquitously, and play essential roles in emb...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9105267/ https://www.ncbi.nlm.nih.gov/pubmed/35565443 http://dx.doi.org/10.3390/cancers14092314 |