CXCR4/CXCL12 Activities in the Tumor Microenvironment and Implications for Tumor Immunotherapy

SIMPLE SUMMARY: Chemokines are small soluble proteins that control and regulate cell trafficking within and between tissues by binding to their receptors. Among them, CXCL12 and its receptor CXCR4 appeared with ancestral vertebrates, are expressed almost ubiquitously, and play essential roles in emb...

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Detalles Bibliográficos
Autores principales: Mezzapelle, Rosanna, Leo, Manuela, Caprioglio, Francesca, Colley, Liam S., Lamarca, Andrea, Sabatino, Lina, Colantuoni, Vittorio, Crippa, Massimo P., Bianchi, Marco E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9105267/
https://www.ncbi.nlm.nih.gov/pubmed/35565443
http://dx.doi.org/10.3390/cancers14092314

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